Research Paper &
Conference Presentation
Research paper/
Conference presentation
We present a comprehensive list of research achievements published as academic papers and conference presentations.
Discover the insights and technological advances gained across our research domains, organized by field and year.
- Research paper
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Conference
presentation
Pursuit of superior flavor and taste
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Time-resolved transcriptomics of S. cerevisiae and S. pastorianus in response to plasma membrane stresses
Sci Data. 2025 Jul 16;12(1):1246 -
Enhanced Production of Rebaudioside D and Rebaudioside M through V155T Substitution in the Glycosyltransferase UGT91D2 from Stevia rebaudiana
J Agric Food Chem. 2025 Jan 22;73(3):2019-2032 -
Combined sensory, volatilome and transcriptome analyses identify a limonene terpene synthase as a major contributor to the characteristic aroma of a Coffea arabica L. specialty coffee
BMC Plant Biol. 2024 Apr 3;24(1):238 -
Functional diversity and plasticity in the sugar preferences of Saccharomyces MALT transporters in domesticated yeasts
FEMS Yeast Res. 2022 Dec 7;22(1):foac055 -
Discovery of natural TRPA1 activators through pharmacophore-based virtual screening and a biological assay
Bioorganic & Medicinal Chemistry Letters Volume 31, 1 January 2021, 127639 -
Evaluation of 3-Methylbutanoic Acid Methyl Ester as a Factor Influencing Flavor Cleanness in Arabica Specialty Coffee
Applied Sciences, June 2021, 11(12), 5413 -
Compromised chitin synthesis in lager yeast affects its Congo red resistance and release of mannoproteins from the cells
FEMS Microbiology Letters, Volume 367, Issue 22, November 2020, fnaa181 -
Key Odorants in Japanese Roasted Barley Tea (Mugi-Cha) - Differences between Roasted Barley Tea Prepared from Naked Barley and Roasted Barley Tea Prepared from Hulled Barley
J. Agric. Food Chem. 2020, 68, 9, 2728-2737 -
Identification of a new class of non-electrophilic TRPA1 agonists by a structure-based virtual screening approach
Bioorganic & Medicinal Chemistry Letters, 30 (2020) 127142 -
Multi-Sip Time-Intensity Evaluation of Retronasal Aroma after Swallowing Oolong Tea Beverage (PDF)
Foods 2018, 7, 177 -
MAL73 , a novel regulator of maltose fermentation, is functionally impaired by single nucleotide polymorphism in sake brewing yeast
PLoS ONE (2018), 13(6): e0198744. -
Oral carbonation modulates subjective appetite and gastric myoelectrical activity in young women
Journal of Nutritional Science and Vitaminology, 63,186-192, 2017 -
Analysis of Active Components on Oral Fat Sensations in Oolong Tea
Food Science and Technology Research, 23(1), 71-78, 2017 -
Volatile Glycosylation：A story of glycosyltransferase for volatiles.
Plant Specialized Metabolism: Genomics, Biochemistry, and Biological Functions. CRC Press, Chapter 11, p257-281. -
Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms.
Endocr J. (2016), 63(8): 715-725 -
Next-generation sequencing analysis of lager brewing yeast strains reveals the evolutionary history of interspecies hybridization
DNA Research 2016 Feb; 23(1): 67-80 -
Identification of 3-Methylbutanoyl Glycosides in Green Coffea Arabica Beans as Causative Determinants for the Quality of Coffee Flavors. (PDF)
Journal of Agricultural Food Chemistry 2015, 63(14), 3742-3751 -
Evaluation of Postprandial Core or Peripheral Temperatures after Oral Stimulation with Carbonated Water Using a Modified Sham-feeding Test
Japan Society of Nutrition and Food Science (published in Japanese) (2014) 67,19-25 -
Evolution and diversity of the 2-oxoglutarate-dependent dioxygenase (2OGD) superfamily in plants
The Plant Journal (2014) 78/2 ,328-343 -
Strategy of Aroma Research in Development of Beverages and Liquor
AROMA RESEARCH (published in Japanese) (2013) No.55, 273-275 -
High-throughput metabolic profiling of diverse green Coffea arabica beans identified tryptophan as a universal discrimination factor of immature beans
PLoS ONE (2013) 8/8 ,70098 -
The Effects of Carbonated Water upon Gastric and Cardiac Activities and Fullness in Healthy Young Women
Journal of Nutritional Science and Vitaminology (2012) 58/5 ,333-338 -
Opponency of astringent and fat sensations
Current Biology (2012) 22/19,R829-R830 -
Genetic Analysis of Chemosensory Traits in Human Twins
Chemical Senses (2012) 37/9 ,869-881 -
The Sg-1 Glycosyltransferase Locus Regulates Structural Diversity of Triterpenoid Saponins of Soybean
The Plant Cell (2012) 24/5 ,2123-2138 -
CYP716A subfamily members are multifunctional enzymes in triterpenoid biosynthesis
Plant and Cell Physiology (2011) 52/12 ,2050-2061 -
Identification of Sc-type ILV6 as a target to reduce diacetyl formation in lager brewers' yeast
Metabolic Engineering (2011) 13/6,638-647
Cutting-edge health innovations
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Estimation and Validation of an Effective Ergothioneine Dose for Improved Sleep Quality Using Physiologically Based Pharmacokinetic Model
Food Sci Nutr. 2025 Jun 5;13(6):e70382 -
Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects
Front Nutr. 2025 Jan 8:11:1470331 -
Respiratory modulation of the heart rate: A potential biomarker of cardiorespiratory function in human
Comput Biol Med. 2024 May:173:108335 -
Predicting habitual water intake from lifestyle questions
Eur Rev Med Pharmacol Sci. 2023 Sep;27(18):8829-8841 -
Randomized, double-blind, crossover, placebo-controlled clinical trial to evaluate the effects of chicken hot water extract on insulin secretion. (PDF)
European Review for Medical and Pharmacological Sciences、26(7), 2422-2430 -
Characteristics of the glycometabolic categories based on the oral glucose tolerance test results in Japanese adults without diabetes (PDF)
Eur Rev Med Pharmacol Sci.26(8), 2765-2774 -
Plasma NfL is associated with mild cognitive decline in patients with diabetes.
Psychogeriatrics.22(3), 353-359 -
Food-derived antioxidant ergothioneine improves sleep difficulties in humans
Journal of Functional Foods, 95(2022), 105165 -
Identifying Glucose Metabolism Status in Nondiabetic Japanese Adults Using Machine Learning Model with Simple Questionnaire.
Comput Math Methods Med. 2022, 1026121 -
Effect of quercetin glycosides on cognitive functions and cerebral blood flow: a randomized, double-blind, and placebo-controlled study (PDF)
European Review for Medical and Pharmacological Sciences, 26(23), 8700-8712 -
Automated Bowel Sound and Motility Analysis with CNN Using a Smartphone
Sensors、23(1), 407 -
Serum lipopolysaccharide-binding protein levels and the incidence of metabolic syndrome in a general Japanese population: the Hisayama Study (PDF)
J Epidemiol. JE20220232 -
Estimation of water intake from food moisture in the Japanese diet using a cooking‐based conversion factor for water content
Journal of Food Science Volume 86(2),12 January 2021, 266-275 -
Validity of a selective recall method for assessing habitual water intake and hydration status
Eur Rev Med Pharmacol Sci. 2021;25(21):6623-6632. -
Characteristics of the Passive Muscle Stiffness of the Vastus Lateralis: A Feasibility Study to Assess Muscle Fibrosis
Int. J. Environ. Res. Public Health 2021, 18(17), 8947 -
Hydrophobic interactions at subsite S1′ of human dipeptidyl peptidase IV contribute significantly to the inhibitory effect of tripeptides
Heliyon Volume 6, Issue 6, June 2020, e04227 -
Identification of compounds in red wine that effectively upregulate aquaporin-3 as a potential mechanism of enhancement of skin moisturizing
Biochemistry and Biophysics Reports Volume 24, December 2020, 100864 -
(+)-Sesamin-oxidizing CYP92B14 shapes specialised lignan metabolism in sesame
The Plant Journal 2020 Nov;104(4):1117-1128. -
Subacute Ingestion of Caffeine and Oolong Tea Increases Fat Oxidation without Affecting Energy Expenditure and Sleep Architecture: A Randomized, Placebo-Controlled, Double-Blinded Cross-Over Trial
Nutrients 2020 Nov 28;12(12):3671. -
Glycoside‐specific glycosyltransferases catalyze regio‐selective sequential glucosylations for a sesame lignan, sesaminol triglucoside
The Plant Journal, 101(5), 2020: 1221-1233 -
Effects of oligomeric proanthocyanidins (OPCs) of red wine to improve skin whitening and moisturizing in healthy women - a placebo-controlled randomized double-blind parallel group comparative study (PDF)
European Review for Medical and Pharmacological Sciences, 2020; 24: 1571-1584 -
Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults
Nutrients, 2020, 12(4), 1191 -
Evaluation and Interpretation of 9 Body Constitution Scores of CCMQ-J by Seven Independent Questionnaires (PDF)
Japanese Journal of Complementary and Alternative Medicine, September 2020; 16(2): 79-93 -
RNA-seq analysis of diet-driven obesity and anti-obesity effects of quercetin glucoside or epigallocatechin gallate in Drosophila adults (PDF)
European Review for Medical and Pharmacological Sciences, 2019; 23: 857-876 -
Green Tea Intake and Risks for Dementia, Alzheimer’s Disease, Mild Cognitive Impairment, and Cognitive Impairment: A Systematic Review
Nutrients 2019, 11(5), 1165 -
Intake of arachidonic acid-containing lipids in adult humans: dietary surveys and clinical trials
Lipids in Health and Disease, volume 18, Article number: 101 (2019) -
A Cross-sectional Study on the Association between the Constitution in Chinese Medicine and the risk factors of Lifestyle Diseases
Japanese journal of complementary and alternative medicine, 16(2) 95-104, 2019 -
De Novo Transcriptomes of Forsythia koreana Using a Novel Assembly Method: Insight into Tissue- and Species-Specific Expression of Lignan Biosynthesis-Related Gene
PLoS ONE 11(10): e0164805 (2016) -
Body Fat Reducing Effect and Safety Evaluation of Long-Term Consumption of Tea Containing Quercetin Glucoside in Obese Subjects.
Japanese Pharmacology & Therapeutics (published in Japanese) (2015) 43/2,181-194 -
Uridine diphoephate glucose:lignan glucosyltransferase activity of UGT71C1 toward pinoresinol and lariciresinol (PDF)
Plant Biotechnology (2014) 31, 561-566 -
A new O -methyltransferase for monolignol synthesis in Carthamum tinctorius (PDF)
Plant Biotechnology (2014) 31, 545-553 -
Expansion of specialized metabolism-related superfamily genes via whole genome duplication during angiosperm evolution (PDF)
Plant Biotechnology (2014) 31, 579-584 -
Identification and characterization of Camellia sinensis glucosyltransferase, UGT73A17: A possible role in flavonol glucosylation (PDF)
Plant Biotechnology (2014) 31, 573-578 -
Mode-of-action and evolution of methylenedioxybridge forming P450s (PDF)
Plant Biotechnology (2014) 31, 493-503 -
Evolution and diversity of the 2-oxoglutarate-dependent dioxygenase (2OGD) superfamily in plants
The Plant Journal (2014) 78/2 ,328-343 -
A novel O-methyltransferase involved in the first methylation step of yatein biosynthesis in Anthriscus sylvestris
Plant Biotechnology (2013) 30 ,375–384 -
Body Fat Reducing Effect of Continuous Consumption of the Beverage Containing Quercetin Glucosides (Enzymatically Modified Isoquercitrin) in Obese Subjects (PDF)
Japanese Pharmacology & Therapeutics (published in Japanese) (2012) 40/10 ,901-914 -
Body Fat Reducing Effect and Safety Evaluation of Long-term Consumption of Green Tea Containing Quercetin Glucoside in Obese Subjects (PDF)
Japanese Pharmacology & Therapeutics (published in Japanese) (2012) 40/6 ,495-503 -
The Sg-1 Glycosyltransferase Locus Regulates Structural Diversity of Triterpenoid Saponins of Soybean
The Plant Cell (2012) 24/5 ,2123-2138 -
Effect of Long-term Intake of "KURO-Oolong tea OTPP" on Body Fat Mass and Metabolic Syndrome Risk in Over Weight Volunteers (PDF)
Japanese Pharmacology & Therapeutics (published in Japanese) (2011) 39/10 ,889-900 -
Effect of Carbonated Beverage Containing Resistant Maltodextrin on Postprandial Serum Triglyceride (PDF)
Japanese Pharmacology & Therapeutics (published in Japanese) (2011) 39/9 ,813-821 -
CYP716A subfamily members are multifunctional enzymes in triterpenoid biosynthesis
Plant and Cell Physiology (2011) 52/12 ,2050-2061 -
Simultaneous quantification of lignans in Arabidopsis thaliana by highly sensitive capillary liquid chromatography-electrospray ionization-ion trap mass spectrometry.
Plant Biotechnology (2011) 28/3 , 287-293 -
Effects of light on production of endogenous and exogenous lignans by Forsythia koreana wildtype and transgenic cells
Plant Biotechnology (2011) 28/3 ,331-337 -
The construction of transgenic Forsythia plants: comparative study of three Forsythia species.
Plant Biotechnology (2011) 28/3 ,273-280 -
Biosynthetic pathway and metabolic engineering of Sesame lignans
Bioindustry by Japan Bioindustry Association (published in Japanese) (2011) 28/12, 5-11 -
Effect of photoperiod on growth of the plants, and sesamin content and CYP81A1 gene expression in the leaves of sesame (Sesamum indicum L.).
Environmental and Experimental Botany (2011) 75, 212-219
Sustainability
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The Morphological Plasticity of Dwarf Bamboo (Pleioblastus chino) Influences Stemflow Generation Under Different Canopy Conditions
Ecohydrology. Volume18, Issue3, April‐May 2025, e70042 -
An Increase in Specific Discharge With Catchment Area Implies That Bedrock Infiltration Feeds Large Rather Than Small Mountain Headwater Streams
Water Resources Research, 56(9), September 2020, e2019WR025658. -
Specific Kieselguhr Increased Hop Yield Over Several Years
Journal of Agricultural Science, Vol. 10, No. 11; 2018: p91 -
How Inter-Basin Transfer of Water Alters Basin Water Stress Used for Water Footprint Characterization
Environments 2018, 5(9), 105 -
Economic aspects of virtual water trade
Environ. Res. Lett. 12(4), 2017 -
Potential Impacts of Food Production on Freshwater Availability Considering Water Sources
Water 2016, 8(4), 163 -
The influence of pruning and harvest timing on hop aroma, cone appearance, and yield
Food Chemistry, Volume 202, 1 July 2016, Pages 15-22 -
Volatile Glycosylation in Tea Plants: Sequential Glycosylations for the Biosynthesis of Aroma β-Primeverosides Are Catalyzed by Two Camellia sinensis Glycosyltransferases
Plant Physiology, Volume 168, Issue 2, June 2015, Pages 464-477 -
Essences in Metabolic Engineering of Lignan Biosynthesis
Metabolites, 5(2), 270-290 (2015) -
The draft genome of hop, an essence of brewing
Plant and Cell Physiology (2015) 56/3,428-441 -
Yeast production using Fed-Batch culture
The Society for Biotechnology (published in Japanese) (2015) 93,32-34 -
Characterization of a trifunctional fatty acid desaturase from oleaginous filamentous fungus Mortierella alpina 1S-4 using a yeast expression system
Journal of Bioscience and Bioengineering (2013) 116/6 ,672-676 -
Enhancement of phosphate absorption by garden plants by genetic engineering - A new tool for phytoremediation
BioMed Research International (2013), Article ID 182032, 7 pages -
Development novel flower color – a road to blue roses
Chemistry and Education (published in Japanese) (2013) 61/9 ,452-453 -
Molecular phylogenetics and gene expression of plant glycosyltransferases for flavonoids
Newsletter & Japanese Society & Enzyme Engineering (published in Japanese) (2012) 67,6-10 -
Convergent evolution of substrate specificity of enzymes involved in specialized metabolisms
Chemistry and biology by Japan Society for Bioscience, Biotechnology and Agrochemistry (published in Japanese) (2012) 50/1,16-22
Flower
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Non-radiate flowers are associated with truncation of the CYCLOIDEA gene in Scaevola aemula (Goodeniaceae)
Sci Rep 15, 26645 (2025) -
Anthocyanin 5,3′-aromatic acyltransferase from Gentiana triflora , a structural insight into biosynthesis of a blue anthocyanin
Phytochemistry 186, 112727, 2021 -
Development of violet transgenic carnations and analysis of inserted transgenes
The Carnation Genome pp 135-146 2020 Springer -
Identification of the genes that regulate ornamental characters using the Rosa multiflora genome database (http://rosa.kazusa.or.jp/)
Acta Horticulturae Book No.1232 (2019) Proceedings of the VII International Symposium on Rose Research and Cultivation, 111-118 -
Identification and Characterization of Novel Nemophila menziesii Flavone Glucosyltransferases that Catalyze Biosynthesis of Flavone 7,4'-O-Diglucoside, a Key Component of Blue Metalloanthocyanins.
Plant and Cell Physiology (2018) 59(10), 2075-2085 -
Molecular cloning of flavonoid biosynthetic genes and biochemical characterization of anthocyanin O -methyltransferase of Nemophila menziesii Hook. and Arn
Plant Biotechnology, 35, 9-16 (2018) -
Physical interactions among flavonoid enzymes in snapdragon and torenia reveal the diversity in the flavonoid metabolon organization of different plant species
The Plant Journal, 2018, 94(2) 372-392 -
Transgenic Research in Floricultural Crops
Genetic Engineering of Horticultural Crops. Academic Press, Elsevier, Chapter 6, pp. 121-136 (2018). -
Genome sequence and analysis of the Japanese morning glory Ipomoea nil
Nature Communications 7, Article number: 13295 (2016) -
Metabolic Engineering of Flower Color Pathways Using Cytochromes P450 (PDF)
Fifty Years of Cytochrome P450 Research (2014), 207-232 (Ed. Yamazaki, Springer) -
Genetic control and evolution of anthocyanin methylation (PDF)
Plant Physiology (2014) 165/3,962-977 -
Protocols for detection of the transgenes and anthocyanidins of the transgenic "Moon" carnations
Japanese Society for Plant Cell and Molecular Biology (published in Japanese) -
Sequence analysis of the genomic of carnation (Dianthus caryophyllus L.)
DNA Research (2014) 2/3 ,231-241 -
A chalcone isomerase-like protein enhances flavonoid production
The Plant Journal (2014) 78/2 ,294-304 -
Creation of blue rose
Japanese Society for Anthocyanins (published in Japanese) -
Genetic engineering of novel bluer colored chrysanthemums produced by dephinidin-based anthocyanin accumulation
Plant and Cell Physiology (2013) 54/10 ,1684-1695 -
Violet Chrysanthemums – Metabolic Engineering of Anthocyanin Biosynthetic Pathway Resulted in Novel Petal Colours
Plant and Cell Physiology (2013) 54/10 ,1696-1710 -
Expression of flavonoid 3',5'-hydroxylase and acetolactate synthase genes in transgenic carnation: Safety
Journal of Agricultural and Food Chemistry (2013) 61/48 ,11711-11720 -
Flower colour and cytochromes P450
Philosophical Transactions B (2013) 368: 20120432 -
GENETIC ENGINEERING OF FLORICULTURAL CROPS: MODIFICATION OF FLOWER COLOUR, FLOWERING AND SHAPE
Acta Horticulturae (2012) 953 ,209-216 -
Functional analysis of Antirrhinum kelloggii flavonoid 3′-hydroxylase and flavonoid 3′,5′-hydroxylase genes; critical role in flower color and evolution in the genus Antirrhinum
Journal of Plant Research (2012) 125/3 ,451-456 -
Development of blue roses and carnations
Plant Molecular Biology (published in Japanese) -
Environmental risk assessment and field performance of rose (Rosa × hybrida) genetically modified for delphinidin production
Plant Biotechnology (2011) 28/2 ,251 -
Molecular based evidence for a lack of gene-flow between Rosa × hybrida and wild Rosa species in Japan
Plant Biotechnology (2011) 28/2 ,245 -
Biochemical and molecular characterization of anthocyanidin/flavonol 3-glucosylation pathways in Rosa × hybrida
Plant Biotechnology (2011) 28/2 ,239 -
Isolation of cDNAs encoding tetrahydroxychalcone 2'-glucosyltransferase activity from carnation, cyclamen, and catharanthus
Plant Biotechnology (2011) 28/2 ,231 -
Morphological changes of Rosa × hybrida by a chimeric repressor of Arabidopsis TCP3
Plant Biotechnology (2011) 28/2 ,149 -
The new FioreDB database provides comprehensive information on plant transcription factors and phenotypes induced by CRES-T in ornamental and model plants
Plant Biotechnology (2011) 28/2 ,123 -
Engineering of the rose flavonoid biosynthetic pathway successfully generated blue-hued flowers accumulating delphinidin.
Plant and Cell Physiology (2007) 48/11 ,1589-1600
Other
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Dynamic patterns of repeats and retrotransposons in the centromeres of Humulus lupulus L.
New Phytol. 2025 Sep;247(6):2766-2780 -
Evolution and functioning of an X-A balance sex-determining system in hops
Nat Plants. 2025 Jul;11(7):1339-1352 -
3D liquid pattern in beverage retained by pseudoplasticity of hydrocolloid polysaccharides
Food Hydrocolloids. Volume 160, Part 1, March 2025, 110767 -
Anthriscus sylvestris Deoxypodophyllotoxin Synthase Involved in the Podophyllotoxin Biosynthesis
Plant Cell Physiol. 2023 Dec 21;64(12):1436-1448 -
The apiosyltransferase celery UGT94AX1 catalyzes the biosynthesis of the flavone glycoside apiin
Plant Physiol. 2023 Oct 26;193(3):1758-1771 -
Drawing 3D fluid patterns in beverages using a robotic nozzle
Journal of Food Engineering. Volume 357, November 2023, 111555 -
Influence of Apple Mosaic Virus on the Growth, Yield, and Qualities of Saaz Hop
Journal of Plant Sciences, 2017 5(5) 152-159 -
Disruption of lig4 improves gene targeting efficiency in the oleaginous fungus Mortierella alpina 1S-4
Journal of Biotechnology, Volume 208, 20 August 2015, Pages 63-69 -
Gene targeting in the oil-producing fungus Mortierella alpina 1S-4 and construction of a strain producing a valuable polyunsaturated fatty acid
Current Genetics, 61, pages579-589 (2015)
